Ontonix srl:: Complexity, drug toxicity and drug design.
Monday, 5 August, 2013 Leave a comment
There exist essentially two approaches to drug toxicity determination: knowledge-based and the QSAR (Quantitative Structure Activity Relationship) rule-based models, which relate variations in biological activity and molecular descriptors. Evidently, any expert of rule-based system will see its efficacy bounded by the quality and relevance of the employed rules. Because of the inability to predict successfully drug toxicity, drug manufacturers report billion-dollar losses every year.